Mycobacterium tuberculosis H37Rv

New website - version 2.6

Release 25 - April 2012



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The current release (R25 - April 2012) contains the updated annotation of the M. tuberculosis H37Rv genome sequence. Some of the notable changes in this release are:

  1. Two new genes have been annotated - Rv2395A and Rv2395B.
  2. A total of 2828 proteins have now been indentified by proteomics studies, of which, 183 previously did not have proteomics annotation in TubercuList.
  3. Links to 44 protein structures in the Protein Data Bank have been added. The structures of 4 proteins are reported for the first time.
  4. Gene essentiality predictions based on transposon mutagenesis and deep-sequencing from the publication by Griffin et al., 2011 have been added.

Quick Search has been modified to correct problems encountered when there are multiple matches to a search term.



TubercuList in numbers:

  • 4,411,532 bp of DNA sequence representing the whole Mycobacterium tuberculosis chromosome (strain H37Rv, EMBL/GenBank/DDBJ entry AL123456)
  • 4,015 protein genes
  • 7 pseudogenes
  • 45 tRNA genes
  • 3 rRNA genes
  • 23 sRNA genes
  • 2 miscRNA genes
  • Gene density: 0.91 genes per kb
  • Average gene length: 1,003 bases per gene
  • Protein coding (CDS) bases: 4,029,225
  • Protein coding percentage: 91.3%
  • GC percentage: 65.9 %
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The TubercuList knowledge base integrates genome details, protein information, drug and transcriptome data, mutant and operon annotation, bibliography, structural views and comparative genomics, in a structured manner required for the rational development of new diagnostic, therapeutic and prophylactic measures against tuberculosis. With the means of expert curation and continuous updates, we deliver a broad view of the Mycobacterium tuberculosis genome.

To Cite TubercuList: Lew JM, Kapopoulou A, Jones LM, Cole ST.
TubercuList - 10 years after.
Tuberculosis (Edinb). Jan 91(1):1-7 (2011)

The TubercuList database and website has been created by and is currently being annotated and maintained in the laboratory of Professor Stewart Cole, part of the Global Health Institute at the Ecole Polytechnique Fédérale de Lausanne, and in collaboration with the Swiss Institute of Bioinformatics.

Submission form for available TB knockouts/mutants

If you have a TB knockout/mutant that you would like to share, please fill out the following form with as much information as you can provide. See a compiled list of all available data here or on the corresponding Gene Pages.

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