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| Functional category | regulatory proteins |
| Proteomics | Identified in the membrane fraction of M. tuberculosis H37Rv using nanoLC-MS/MS; predicted integral membrane protein (See Xiong et al., 2005). |
| Transcriptome | mRNA identified by microarray analysis and down-regulated after 4h, 24h and 96h of starvation (see Betts et al., 2002). |
| Mutation | non essential gene by Himar1-based transposon mutagenesis in H37Rv strain (see Sassetti et al., 2003). Required for survival in primary murine macrophages, by transposon site hybridization (TraSH) in H37Rv (See Rengarajan et al., 2005). mutants available at TARGET website |
| Coordinates | |||
|---|---|---|---|
| Type | Start | End | Orientation | CDS | 21637 | 23181 | - |
| Protein sequence in FASTA format | ||
|---|---|---|
| >M. tuberculosis H37Rv | pstP MARVTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVASQLVIAALAHLDDDEPGGDLLAKLDAAVRAG NSAIAAQVEMEPDLEGMGTTLTAILFAGNRLGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITPEEAHSHPQRS LIMRALTGHEVEPTLTMREARAGDRYLLCSDGLSDPVSDETILEALQIPEVAESAHRLIELALRGGGPDNVTVVVADVVD YDYGQTQPILAGAVSGDDDQLTLPNTAAGRASAISQRKEIVKRVPPQADTFSRPRWSGRRLAFVVALVTVLMTAGLLIGR AIIRSNYYVADYAGSVSIMRGIQGSLLGMSLHQPYLMGCLSPRNELSQISYGQSGGPLDCHLMKLEDLRPPERAQVRAGL PAGTLDDAIGQLRELAANSLLPPCPAPRATSPPGRPAPPTTSETTEPNVTSSPASPSPTTSAPAPTGTTPAIPTSASPAA PASPPTPWPVTSSPTMAALPPPPPQPGIDCRAAA | ||
| Blastp: results | ||
| TransMembrane prediction using Hidden Markov Models: tmhmm | ||
| Microbe Genome Browser | ||
| Genomic sequence | ||
| Structural information | ||
|---|---|---|
| Protein Data Bank | 1TXO 2CM1 | |
| PFAM | Protein Family Domains | |
| 3D Structure Viewer |
| Orthologs/Cross-references | ||
|---|---|---|
| CDC1551 | MT0021 | |
| Enzyme Classification | 3.1.3.16 | |
| Gene Ontology | phosphoprotein phosphatase activity plasma membrane integral to membrane manganese ion binding | |
| Mbovis | Mb0018c | |
| Mleprae | ML0020 | |
| Mmarinum | MMAR_0020 | |
| Msmegmatis | MSMEG_0033 | |
| UniProt | P71588 | |
| Interacting Drugs/Compounds | ||
|---|---|---|
| TDR Targets | Rv0018c | |
| Expression Data | ||
|---|---|---|
| TBDB | Rv0018c | |