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Search term: Rv2231B

General annotation | Coordinates | Sequence | Structural information | Orthologs/Cross-references | Interacting Drugs/Compounds | Bibliography
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General annotation
Gene namevapB16
Rv numberRv2231B
ProductPossible antitoxin VapB16
CommentsRv2231B, len: 58 aa. Possible vapB16, antitoxin, part of toxin-antitoxin (TA) operon with Rv2231A (See Pandey and Gerdes, 2005).
Molecular mass (Da)6490.67
Isoelectric point11.2008
Gene length (bp)177
Protein length58
Location (kb)2506.21

Functional categoryvirulence, detoxification, adaptation

Mutation Check for mutants available at TARGET website


Protein sequence in FASTA format
>M. tuberculosis H37Rv|Rv2231B|vapB16
Blastp: Pre-computed results
TransMembrane prediction using Hidden Markov Models: TMHMM
Genomic sequence

Add extra bases upstream (5') and downstream (3')

Multiple Sequences Alignment: between orthologs

Interacting Drugs/Compounds
TDR TargetsRv2231B

Expression Data

Pandey DP, Gerdes K,
Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes.
Nucleic Acids Res (2005) 33(3):966-76
Cited for: Homology
Gupta A,
Killing activity and rescue function of genome-wide toxin-antitoxin loci of Mycobacterium tuberculosis.
FEMS Microbiol Lett (2009) 290(1):45-53
Cited for: Function
Ramage HR, Connolly LE, Cox JS,
Comprehensive functional analysis of Mycobacterium tuberculosis toxin-antitoxin systems: implications for pathogenesis, stress responses, and evolution.
PLoS Genet (2009) 5(12):e1000767
Cited for: Function