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Search term: Rv1028A

General annotation | Coordinates | Sequence | Structural information | Orthologs/Cross-references | Interacting Drugs/Compounds | Bibliography
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General annotation
Gene namekdpF
Rv numberRv1028A
FunctionThought to be involved in stabilization of the KDP complex.
ProductProbable membrane protein KdpF
CommentsRv1028A, len: 30 aa. Probable kdpF, membrane protein, showing similarity with P36937|KDPF_ECOLI|B0698.1 protein KDPF from Escherichia coli strain K12 (see citation below) (27% identity); and KdpF protein from Streptomyces coelicolor (51% identity).
Molecular mass (Da)3256.01
Isoelectric point4.1843
Gene length (bp)93
Protein length30
Location (kb)1151.92

Functional categorycell wall and cell processes

MutationNon-essential gene for in vitro growth of H37Rv, by sequencing of Himar1-based transposon mutagenesis (See Griffin et al., 2011). Check for mutants available at TARGET website


Protein sequence in FASTA format
>M. tuberculosis H37Rv|Rv1028A|kdpF
Blastp: Pre-computed results
TransMembrane prediction using Hidden Markov Models: TMHMM
Genomic sequence

Add extra bases upstream (5') and downstream (3')

Structural information
Protein Data BankNo structure available

M. bovisMb1057
Multiple Sequences Alignment: between orthologs

Interacting Drugs/Compounds
TDR TargetsRv1028A

Expression Data

Gassel M, Mollenkamp T, Puppe W, Altendorf K,
Analysis of KdpC of the K(+)-transporting KdpFABC complex of Escherichia coli
Eur J Biochem (2001) 268(6):1772-81
Cited for: Homolog/Function
Li C, Gao P, Qin H, Chase R, Gor'kov PL, Brey WW, Cross TA,
Uniformly aligned full-length membrane proteins in liquid crystalline bilayers for structural characterization.
J Am Chem Soc (2007) 129(17):5304-5
Cited for: Structure
Griffin JE, Gawronski JD, Dejesus MA, Ioerger TR, Akerley BJ, Sassetti CM,
High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism.
PLoS Pathog (2011) 7(9):e1002251
Cited for: Mutant